Daily Rules, Proposed Rules, and Notices of the Federal Government
The report and recommendations have been transmitted to Federal agencies for their review and response to ICCVAM.
The process for developing the ICCVAM recommendations began with a critical review of the analysis (Haseman
ICCVAM considered the analysis (Haseman
ICCVAM is an interagency committee composed of representatives from 15 Federal regulatory and research agencies that require, use, generate, or disseminate toxicological and safety testing information. ICCVAM conducts technical evaluations of new, revised, and alternative safety testing methods and integrated testing strategies with regulatory applicability and promotes the scientific validation and regulatory acceptance of testing methods that more accurately assess the safety and hazards of chemicals and products and that reduce, refine (enhance animal well-being and lessen or avoid pain and distress), or replace animal use. The ICCVAM Authorization Act of 2000 (42 U.S.C. 285
SACATM was established in response to the ICCVAM Authorization Act (Section 285
CPSC. 2010. Federal Hazardous Substances Act Regulations. 16 CFR 1500. Available:
Haseman J.K., Allen D.G., Lipscomb E.A., Truax J.F., Stokes WS. 2011. Using fewer animals to identify chemical eye hazards: revised criteria necessary to maintain equivalent hazard classification. Regul Toxicol Pharmacol 61: 98-104.